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Home > Safety

Adverse events were comparable between JAKAVI and BAT in both acute and chronic GvHD1

Commonly reported adverse events from the REACH2 trial
Commonly reported adverse events from the REACH3 trial

JAKAVI maintained a safety profile in SR GvHD consistent with over 10 years of
real-world experience in MF and PV1-3

References
  1. JAKAVI® (ruxolitinib) tablets: EU Summary of Product Characteristics. Novartis; January 2022.
  2. Zeiser R, von Bubnoff N, Butler J, et al; REACH2 Trial Group. Ruxolitinib for glucocorticoid-refractory acute graft-versus-host disease. N Engl J Med. 2020;382(19):1800-1810.
  3. Zeiser R, Polverelli N, Ram R, et al; REACH3 Investigators. Ruxolitinib for glucocorticoid-refractory chronic graft-versus-host disease. N Engl J Med. 2021;385(3):228-238.