Inability to achieve and consistently maintain haematocrit <45% can have serious consequences
Even moderate increases in haematocrit levels (45%-50%) were associated with significant increases in risk of major events1
Increased risks with elevated haematocrit despite phlebotomy and/or cytoreductive therapy1

Elevated risk was observed in the high haematocrit group (median haematocrit of 47.5%) compared with the low haematocrit group (median of 44.4%)1
- Supplemental phlebotomy may not consistently maintain target haematocrit levels2